I thought the point of Focusrite's Clarett line was zero latency via thunderbolt. This looks like a re-badged Scarlett with a fancier GUI and a new DSP algorithm to emulate the ISA1. There's no latency advantage here. You still need to do direct monitoring from what I can see. Focusrite is really getting more and more into the smoke and mirrors game.
I'm still using a Saffire unit that works perfectly.
https://www.sweetwater.com/insync/focusrite-announces-clarett-usb-interfaces/?utm_content=article1-button&utm_source=insync&utm_medium=email&utm_campaign=20180113